Studi scientifici

Ricercatrice sorridente

Da più di 20 anni il centro internazionale di ricerca Danone Research lavora a stretto contatto con le strutture cliniche più avanzate e le associazioni di professionisti più affermate, per sviluppare alimenti specifici di qualità altissima e per studiarne costantemente le proprietà.

Su Activia sono stati condotti 16 studi scientifici, che hanno coinvolto più di 1200 persone in 6 differenti paesi

Di seguito i riferimenti bibliografici di questi studi, aggregati per argomento:

•Studi clinici pubblicati relativi alla sopravvivenza del the Bifidobacterium lactis DN-173010 nel tratto gastrointestinale

Rochet V., L. Rigottier-Gois, A. Ledaire, C. Andrieux, M. Sutren, S. Rabot, A. Mogenet, J-L Bresson, S. Cools, C. Picard, N. Goupil-Feuillerat and J. Doré. Survival of Bifidobacterium animalis DN-173 010 in the faecal microbiota after administration in lyophilised form or in fermented product - a randomised study in healthy adults. Journal of Molecular Microbiology and Biotechnology, 2008;14: 128-136.

He T., M. G. Priebe, Y. Zhong, C. Huang, H.J.M. Harmsen, G.C. Raangs, J.M. Antoine, G.W. Welling and R.J. Vonk. Effect of yogurt and bifidobacteria supplementation on the colonic microbiota in lactose-intolerant subjects. Journal of Applied Microbiology, 2007; 104(2):595-604.

Collado M.C., Y. Moreno, J..M. Cobo, J.A. Mateos, M. Hernandez. Molecular detection of Bifidobacterium animalis DN-173 010 in human feces during fermented milk administration.
Food Research International, 2006; 39: 530-535.

Duez H., Pelletier C., Cools S., Aissi E., Cayuela C., Gavini F., Bouquelet S., Neut C. and Mengaud J. A colony-immunoblotting method for quatitative detection of a Bifidobacterium animalis probiotic strain in human faeces. Journal of Applied Microbiology, 2000; 88:1019-27.

Pochart P., Marteau P., Bouhnik Y., Goderet I., Bourlioux P., Rambaud J.C. Survival of Bifidobacteria ingested via fermented milk during their passage through the human small intestine: an in vivo study using intestinal perfusion. American Journal of Clinical Nutrition, 1992; 55:78-80.

Berrada N., Lemeland J.F., Laroche G., Thouvenot P., Piaia M. Bifidobacterium from fermented milks: Survival during gastric transit. Journal of Dairy Science, 1991; 74:409-413.

Pochart P., Marteau P., Bisetti N., Goderet I., Bourlioux P., Rambaud J.C.
Isolement des bifidobactéries dans les selles après ingestion prolongée de lait au bifidus (LB).
No abstract available Médecine et Maladies Infectieuses 1990; 20: 75-78 (publication in French).


•Studi sugli effetti del Bifidobacterium lactis DN-173010 sul transito gastrointestinale
 
Nishida S., Ishikawa Y., Iino H. Effect of Bifidobacterium lactis DN-173 010 on the Intestinal Transit Time, the Condition of Defecation and Intestinal Microflora: A randomized, Double-blind, Placebo-controlled, Cross-over Study among Healthy Japanese Women. Pharmacometrics 2008;74 (5/6): 99-106.

Méance S., Cayuela C., Raimondi A., Turchet P., Lucas C. and Antoine J.M. Recent advances in the use of functional foods: effects of the commercial fermented milk with Bifidobacterium animalis strain DN-173 010 and yoghurt strains on gut transit time in the elderly. Microbial Ecology in Health and Disease 2003; 15: 15-22.

Marteau P., Cuillerier E., Méance S., Gerhardt M.F., Myara A., Bouvier M., Bouley C., Tondu F., Bommelaer G., Grimaud J.C. Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women : a double blind, randomized, controlled study. Alimentary Pharmacology and Therapeutics, 2002; 16: 587-593.

Méance S., Cayuela C., Turchet P., Raimondi A., Lucas C. and Antoine J.M. A fermented milk with a Bifidobacterium probiotic strain DN-173 010 shortened oro-fecal gut transit time in elderly. Microbial Ecology in Health and Disease. 2001; 13: 217-222.

Bouvier M, Méance S, Bouley C, Berta JL and Grimaud JC. Effect of consumption of a milk fermented by the probiotic strain Bifidobacterium animalis DN-173 010 on colonic transit time in healthy humans. Bioscience Microflora. 2001; 20 (2): 43-48.

Yang Y., He M., Hu G., Wei J., Pages P., Yang X., Bourdu-Naturel S. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on Chinese constipated women. World Journal of Gastroenterology, 2008; 14(40): 6237-6243.


•Studi sugli effetti del Bifidobacterium lactis DN-173010 sul benessere gastrointestinale
 
Guyonnet D., Woodcock A., Stefani B., Trevisan C. and Hall C.
Fermented milk containing Bifidobacterium lactis DN-173 010 improved self-reported digestive comfort amongst a general population of adults. A randomized, open-label, controlled, pilot study. Journal of Digestive Diseases, 2009; 10: 61-70.

Agrawal A., Houghton L.A., Morris J., Reilly B.,D., Guyonnet D., Goupil-Feuillerat N., Schlumberger A., Jakob S. & Whorwell P.J. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173-010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Alimentary Pharmacology and Therapeutics, 2009; 29(1): 104-114.

Guyonnet D, O. Chassany, P. Ducrotte, C. Picard, M. Mouret, C.H. Mercier and C. Matuchansky.
Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel symdrome adults in primary care. A multicentre, randomised, double-blind, controlled trial.Alimentary Pharmacology and Therapeutics, 2007; 26 (3): 475-486.

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